, or buffalo, were slaughtered for skins and meat and to ease the railways' spread. The loss of the buffalo, a primary resource for the 
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Civil War and industrialization
Tensions between slave and free states mounted with arguments about the relationship between the state and federal governments, as well as violent conflicts over the spread of slavery into new states. Abraham Lincoln, candidate of the largely antislavery Republican Party, was elected president in 1860. Before he took office, seven slave states declared their secession—which the federal government maintained was illegal—and formed the Confederate States of America. With the Confederate attack upon Fort Sumter, the Civil War began and four more slave states joined the Confederacy. Lincoln's Emancipation Proclamation in 1863 declared slaves in the Confederacy to be free. Following the Union victory in 1865, three amendments to the U.S. Constitution ensured freedom for the nearly four million African Americans who had been slaves, made them citizens, and gave them voting rights. The war and its resolution led to a substantial increase in federal power. The war remains the deadliest conflict in American history, resulting in the deaths of 620,000 soldiers.
After the war, the assassination of Abraham Lincoln radicalized Republican Reconstruction policies aimed at reintegrating and rebuilding the Southern states while ensuring the rights of the newly freed slaves. The resolution of the disputed 1876 presidential election by the Compromise of 1877 ended Reconstruction; Jim Crow laws soon disenfranchised many African Americans. In the North, urbanization and an unprecedented influx of immigrants from Southern and Eastern Europe hastened the country's industrialization. The wave of immigration, lasting until 1929, provided labor and transformed American culture. National infrastructure development spurred economic growth. The 1867 Alaska Purchase from Russia completed the country's mainland expansion. The Wounded Knee Massacre in 1890 was the last major armed conflict of the Indian Wars. In 1893, the indigenous monarchy of the Pacific Kingdom of Hawaii was overthrown in a coup led by American residents; the United States annexed the archipelago in 1898. Victory in the Spanish–American War the same year demonstrated that the United States was a world power and led to the annexation of Puerto Rico, Guam, and the Philippines. The Philippines gained independence a half-century later; Puerto Rico and Guam remain U.S. territories.
World War I, Great Depression, and World War II
At the outbreak of World War I in 1914, the United States remained neutral. Most Americans sympathized with the British and French, although many opposed intervention. In 1917, the United States joined the Allies, and the American Expeditionary Forces helped to turn the tide against the Central Powers. After the war, the Senate did not ratify the Treaty of Versailles, which established the League of Nations. The country pursued a policy of unilateralism, verging on isolationism. In 1920, the women's rights movement won passage of a constitutional amendment granting women's suffrage. The prosperity of the Roaring Twenties ended with the Wall Street Crash of 1929 that triggered the Great Depression. After his election as president in 1932, Franklin D. Roosevelt responded with the New Deal, a range of policies increasing government intervention in the economy, including the establishment of the Social Security system. The Dust Bowl of the mid-1930s impoverished many farming communities and spurred a new wave of western migration.
The United States, effectively neutral during World War II's early stages after Nazi Germany's invasion of Poland in September 1939, began supplying materiel to the Allies in March 1941 through the Lend-Lease program. On December 7, 1941, the Empire of Japan launched a surprise attack on Pearl Harbor, prompting the United States to join the Allies against the Axis powers as well as the internment of Japanese Americans by the thousands. Participation in the war spurred capital investment and industrial capacity. Among the major combatants, the United States was the only nation to become richer—indeed, far richer—instead of poorer because of the war. Allied conferences at Bretton Woods and Yalta outlined a new system of international organizations that placed the United States and Soviet Union at the center of world affairs. As victory was won in Europe, a 1945 international conference held in San Francisco produced the United Nations Charter, which became active after the war. The United States, having developed the first nuclear weapons, used them on the Japanese cities of Hiroshima and Nagasaki in August. Japan surrendered on September 2, ending the war.
Cold War and protest politics
The United States and the Soviet Union jockeyed for power after World War II during the Cold War, dominating the military affairs of Europe through NATO and the Warsaw Pact, respectively. While they engaged in proxy wars and developed powerful nuclear arsenals, the two countries avoided direct military conflict. Resisting leftist land and income redistribution projects around the world, the United States often supported authoritarian governments. American troops fought Communist Chinese forces in the Korean War of 1950–53. The House Un-American Activities Committee pursued a series of investigations into suspected leftist subversion, while Senator Joseph McCarthy became the figurehead of anticommunist sentiment.
The 1961 Soviet launch of the first manned spaceflight prompted President John F. Kennedy's call for the United States to be first to land "a man on the moon", achieved in 1969. Kennedy also faced a tense nuclear showdown with Soviet forces in Cuba. Meanwhile, the United States experienced sustained economic expansion. A growing civil rights movement, symbolized and led by African Americans such as Rosa Parks and Martin Luther King, Jr., used nonviolence to confront segregation and discrimination. Following Kennedy's assassination in 1963, the Civil Rights Act of 1964 and Voting Rights Act of 1965 were passed under President Lyndon B. Johnson. He also signed into law the Medicare and Medicaid programs. Johnson and his successor, Richard Nixon, expanded a proxy war in Southeast Asia into the unsuccessful Vietnam War. A widespread countercultural movement grew, fueled by opposition to the war, black nationalism, and the sexual revolution. Betty Friedan, Gloria Steinem, and others led a new wave of feminism that sought political, social, and economic equality for women.
As a result of the Watergate scandal, in 1974 Nixon became the first U.S. president to resign, to avoid being impeached on charges including obstruction of justice and abuse of power. The Jimmy Carter administration of the late 1970s was marked by stagflation and the Iran hostage crisis. The election of Ronald Reagan as president in 1980 heralded a rightward shift in American politics, reflected in major changes in taxation and spending priorities. His second term in office brought both the Iran-Contra scandal and significant diplomatic progress with the Soviet Union. The subsequent Soviet collapse ended the Cold War.
Contemporary era
Under President George H. W. Bush